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Global Health Action

Informa UK Limited

Preprints posted in the last 90 days, ranked by how well they match Global Health Action's content profile, based on 10 papers previously published here. The average preprint has a 0.01% match score for this journal, so anything above that is already an above-average fit.

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Food insecurity as a determinant of adolescent mental health in Francophone and Anglophone Africa: A multilevel analysis

Fonta, C. L.; Elgar, F.; Gordon, D.; Toumpakari, Z.

2026-05-25 public and global health 10.64898/2026.05.19.26353168 medRxiv
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Food insecurity (also called, simply, FI) levels in sub-Saharan Africa are rising among its growing adolescent population, the world's fastest-growing teenage population. This study examines food insecurity and its role as a social determinant of poor mental health among African adolescents. The study utilised the Gallup World Poll data between 2014 and 2019, including adolescents aged 15 -19 (n=25,368). Poor mental health was measured using five validated responses about negative experiences. We employed a two-level binary logistic regression model to determine the associations between food insecurity and poor mental health. At the individual level, the primary explanatory variable, food insecurity, was measured using the FAO (2015) Food Insecurity Experience Scale (FIES). The odds of poor mental health exhibited a dose-response relationship with food insecurity severity, with mild (OR=1.70; 95% CI (1.57-1.84), moderate (OR=2.35; 95% CI (2.17-2.54) and severe food insecurity (OR=3.19; 95% CI (2.96-3.54) being associated with poorer mental health. Other assessed covariates showed that residing in a Francophone state increased the odds of poor mental health experiences, whereas positive experiences reduced the chances of poor mental health, as did residing in rural areas. There was no difference in the relationship between mental health and food insecurity across the two colonial origins. Food insecurity remains an important determinant of adolescent mental health in Francophone and Anglophone Africa. Investing in cost-effective agricultural and nutrition-sensitive interventions that boost food production could improve adolescent mental well-being while reducing long-term social and economic burdens on families and health systems in sub-Saharan Africa.

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Impact of Out-Migration and Remittances on Food Consumption Outcomes among Rural Households in Tigray, Ethiopia

Weldu, T. T.

2026-06-11 nutrition 10.64898/2026.06.09.26355307 medRxiv
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This study examines the effects of rural out-migration and remittance inflows on food consumption outcomes among rural households in the Tigray region of Ethiopia. Utilizing household survey data collected from 521 rural households across three distinct Weredas (districts) (Tahtay Maichew, Kola Tembien, and Kilte-awlaelo). A Binary Probit model was employed to identify factors influencing migration decisions, while an Endogenous Switching Regression (ESR) model was used to estimate the impact of migration on food consumption outcomes while controlling for selection bias and unobserved heterogeneity. Food security was measured using the Food Consumption Score (FCS) and dietary diversity indicators. The empirical results reveal that severe food insecurity is widespread, with over 60% of all surveyed households falling into the "Poor" food consumption category. Descriptive baseline comparisons show that migration and remittance transfers marginally shift the raw average FCS upward from 23.86 to 25.48. However, this impact is profoundly nuanced: remittances serve as an immediate consumption-smoothing safety net but run parallel to a "labor-lost" constraint that reduces own-production capacities, forcing households to rely increasingly on market purchases for staple foods. The findings reveal that migration creates short-term labor shortages in agricultural production; however, remittance inflows substantially improve household food consumption frequencies, particularly for pulses, vegetables, and other nutrient-rich foods. After accounting for self-selection bias and unobserved traits, the rigorous ESR estimates indicate that migration increases the Food Consumption Score of participating households by an average Treatment Effect on the Treated (ATT) of 10.75 points, shifting them into more secure dietary tiers. Moreover, remittances help households mitigate the adverse effects of drought and other shocks by relaxing liquidity constraints and supporting both food purchases and agricultural investments. The study recommends establishing target food security safety nets for non-remittance households, promoting scale-appropriate labor-saving agricultural technologies, expanding traditional communal labor-sharing innovations, and boosting irrigation and agricultural input support programs to enhance rural food security and livelihood resilience.

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Assessment Of Household Food Security and Nutritional Status of Mother-Child Pair in Selected Local Government Areas in Ondo State.

Gbayisemore, E. E.; AJAYI, K.; ALEBIOSU, I. A.; OGUNETIMOJU, A. M.

2026-05-01 nutrition 10.64898/2026.04.29.26352102 medRxiv
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IntroductionFood insecurity and mixed patterns of malnutrition coexist in rural Nigeria despite the countrys agricultural potential. There is a lack of precise data regarding the relationship between household food security and nutritional status of the mother-child pair in southwestern Nigeria. This study examined household food security and mother-child nutritional status in Irele and Okitipupa Local Government Areas (LGAs) of Ondo State. Methods and AnalysisA descriptive cross-sectional community-based survey was carried out with 358 mother-child pairs (children 6-59 months). The Household Food Insecurity Access Scale (HFIAS) was used to measure household food insecurity. Body Mass Index (BMI) was used to assess mothers and WHO Anthro Z-scores to assess childrens nutritional status. Descriptive statistics and Chi-square tests (p < 0.05) were used to examine the data. Results93.3% of households were food insecure. A striking double burden of malnutrition was observed: 58.4% of mothers were overweight or obese, and child malnutrition was widespread, with 39.3% stunting, 29.1% wasting and 42.1% underweight. Breastfeeding duration (p = 0.008) and introduction of complementary feeding (p = 0.032) were significant predictors of child wasting. Interestingly, maternal education and income were not significant predictors of child undernutrition (p > 0.05), suggesting that environmental and behavioral influences take precedence over individual socioeconomic status in these communities ConclusionThe simultaneous presence of severe child undernutrition and maternal overnutrition in rural Ondo State suggests a public health crisis in a state undergoing nutrition transition towards energy-dense, low-nutrient foods. These results suggest that national approaches are inadequate. We need interventions that focus on decentralized, LGA-level policies that integrate food security programs with education on Infant and Young Child Feeding (IYCF). What is already known on this topicHousehold food insecurity is a major driver of malnutrition among mothers and children under five in Nigerias rural communities. Evidence from southwestern Nigeria shows that over 88% of rural households are food insecure, with women and young children disproportionately affected. However, localized data from specific LGAs in Ondo State--particularly examining the mother-child dyad--remains scarce. What this study addsThis study provides the first localized evidence from Irele and Okitipupa LGAs, Ondo State, documenting a 93.3% household food insecurity rate and a dual burden of malnutrition (39.3% child stunting and 58.4% maternal overweight/obesity coexisting in the same communities). It demonstrates that IYCF practices--specifically breastfeeding duration and timing of complementary food introduction--are significant determinants of child wasting, and highlights the limitations of maternal socioeconomic variables alone as predictors of child nutritional outcomes. How this study might affect research, practice or policyFor research, this study establishes a dyadic methodological framework applicable to other Nigerian states. For practice, it underscores that nutrition education on IYCF practices must accompany food security programs. For policy, the findings call for decentralized, LGA-specific strategies addressing both rural food insecurity and the emerging nutrition transition--moving beyond one-size-fits-all national approaches to combat simultaneous undernutrition and overnutrition within the same households.

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Fetal malnutrition and its predictors among term newborns in southern Ethiopia: a multicenter cross-sectional study

Yeheyis, T.; Likka, M. H.

2026-06-29 nutrition 10.64898/2026.06.24.26356480 medRxiv
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Introduction: Low and middle-income countries suffer from a high burden of undernutrition. Fetal malnutrition negatively impacts a newborn's body composition, metabolism, and enzymatic processes, predisposing the newborn to malnutrition during childhood period. This study aims to assess the magnitude of fetal malnutrition and its predictors in southern Ethiopia. Methods: A facility-based cross-sectional study was conducted among 423 pairs of mother and term newborn delivered from February 1- 28, 2025, at five randomly selected public hospitals in southern Ethiopia. The Clinical Assessment of Nutrition (CAN) Score is used to assess fetal malnutrition. Logistic regression was employed to identify predictors of fetal malnutrition. Statistical significance of the association was declared at p < 0.05. Results: Among 423 newborns included in the study, 60 (14.1%) had fetal malnutrition. Newborns born to women with a placental weight of 519 grams or less had ten times higher odds of fetal malnutrition compared to their counterparts (AOR=9.795, 95% CI: 4.881-19.657). Dietary counselling during pregnancy reduced odds of fetal malnutrition by 62.3% (AOR=0.377, 95% CI: 0.162-0.877); similarly, an extra meal during pregnancy was associated with reduced odds of fetal malnutrition by 71.6% (AOR=0.284, 95% CI: 0.131-0.616). Newborns delivered from women who had a MUAC (Mid Upper Arm Circumference) >22 cm had 75.7% lower odds of fetal malnutrition (AOR=0.243, 95% CI 0.074 -0.797), whereas maternal chronic medical illness increased the odds by threefold (AOR=3.419, 95% CI: 1.269-9.153). Conclusion: There is a high magnitude of fetal malnutrition in the study area. Placental weight, dietary counselling, extra meals during pregnancy, MUAC and chronic medical illness were predictors of fetal malnutrition, signifying the need for a comprehensive approach targeting maternal nutrition during pregnancy

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Magnitude of Undernutrition and Associated Factors among Pregnant Women Attending Public Health Facilities in Goba District, Bale Zone, Oromia, Ethiopia: A cross-sectional Study,

Ibrahim, S. M.; Lakew, M. S.; Amhare, A. F.; Hussein, D.; Kedir, H.; Abdulbesit, H.

2026-06-08 nutrition 10.64898/2026.06.05.26354999 medRxiv
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Abstract Objective: This study aimed to assess the magnitude of undernutrition and associated factors among pregnant women attending public health facilities in the Goba district, Bale zone, Oromia Region, Ethiopia, 2022. Design: Institution-based, cross-sectional study design was used. Setting: The study was conducted in selected public health facilities from May to June 2022. Participants: The study population consisted of pregnant women who lived for at least 6 months in the study area and who attended antenatal care follow-up at selected public health facilities during the study period. Pregnant women who lived for less than six months in the study area and those who were critically ill were excluded from the study. Results: 487 respondents participated in this study with a 100% response rate. More than half (50.7%) of pregnant mothers were undernourished. The significant factors associated with maternal undernutrition during pregnancy in this study were mothers with no formal education (AOR = 5.050; 95% CI: 1.470- 17.346), a history of illness during pregnancy (AOR = 2.089; 95% CI: 1.246-3.504), and eating frequency of meals less than or equal to three times per day (AOR = 3.292; 95% CI: 1.040- 10.42). Poor nutritional knowledge (AOR = 5.588; 95% CI: 2.921-10.689), poor household (HH) wealth status (AOR = 4.774; 95% CI: 2.216- 10.285), and mothers who had >= 4 pregnancies were included (AOR = 0.852; 95% CI: 342-0.989). Conclusion: The magnitude of Undernutrition among pregnant women was 50.7%. Significant associations with Undernutrition were found in mothers with no formal education, poor dietary knowledge, a meal frequency of three or fewer times per day, a history of illness during pregnancy, lower and medium household wealth status, and those who had experienced four or more pregnancies while attending antenatal care (ANC) services at public health facilities.

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Mapping Human Development Index and Nutritional Status: Identifying Factors Associated with Malnutrition in Indonesia

Amelia, F.; Ihsani, A. N.; Saputra, Y. A.; Siregar, R. U. P.

2026-07-01 nutrition 10.64898/2026.06.24.26355946 medRxiv
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Background: Indonesia, as an upper-middle-income country, is undergoing a nutrition transition. The persistent problem of undernutrition is now accompanied by rising overnutrition, creating a double burden of malnutrition. The Human Development Index (HDI) that measures socio-economic development, has shown steady improvements in Indonesia, yet nutritional disparities remain across provinces with varying HDI levels. Objective: This study aims to map the relationship between HDI and nutritional status by analyzing the prevalence of stunting, wasting, underweight, and overweight across different HDI categories and provinces in Indonesia. Additionally, this study explores the determinants of malnutrition to provide a deeper understanding of the factors influencing child nutrition status. Methods: This ecological study utilizes data from 2023 Indonesian Nutrition Status Study, Central Bureau of Statistics and Indonesian Demographic and Health Survey and creates provincial level dataset with malnutrition prevalence, HDI, and other health indicators. The analysis employs spatial relationship, descriptive statistics, and correlation analysis to assess the determinants of malnutrition. This ecological study used 2023 provincial-level data from the Indonesian Health Survey (SKI) and the Human Development Index (HDI) published by the Central Bureau of Statistics. Nutritional indicators (stunting, underweight, wasting, and overweight) were analyzed in relation to HDI and other determinants. Spearmans correlation and Mann-Whitney U tests were used for statistical analysis. Spatial patterns were visualized through GIS mapping to explore geographic relationships between HDI levels and nutritional status. Results: Provinces with high to very high HDI had significantly lower prevalence of stunting (21.36% vs. 31.80%), underweight (16.60% vs. 21.89%), and wasting (9.49% vs. 13.00%) compared to those with low to medium HDI (p < 0.05). No significant difference was found for overweight. Significant negative correlations were observed between stunting, underweight, and wasting with several key determinants, including exclusive breastfeeding, proper infant and young child feeding practices, adequate vitamin A intake, proper handwashing and sanitation practices, parental education, immunization coverage, and HDI. However, no significant correlations were found between these determinants and overweight. Conclusion: This study highlights the complex relationship between HDI and nutritional status, emphasizing the need for region-specific interventions. While improving HDI can help to reduce undernutrition, rising overweight prevalence requires targeted public health strategies. These findings offer valuable insights for policymakers to design holistic, multi-dimensional approaches to combat malnutrition in Indonesia. Keywords: Human Development Index, Nutritional Status, Spatial Analysis, Malnutrition, Indonesia

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Creating Equity? A Process Evaluation of Jamkesus Disabilitas, A Disability-Focused Health Financing Scheme in Yogyakarta, Indonesia

Azizatunnisa', L.; Kuper, H.; Probandari, A.; Banks, L. M.

2026-07-01 health systems and quality improvement 10.64898/2026.06.29.26356885 medRxiv
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Background This study aims to explore the initiation and implementation of Jamkesus Disabilitas, a health financing scheme for people with disabilities in Yogyakarta Province, using the UK Medical Research Council (MRC) Process Evaluation for Complex Intervention. Methods We interviewed 19 people with disabilities with different types of impairment as beneficiaries, 3 people from Organisations for People with Disabilities (OPDs), 4 government officials, and 4 health providers, either in person, online, or by phone. Interviews were conducted by LA, and took place in Yogyakarta Province in July-September 2024. Data were analysed using a thematic analysis approach using NVivo 15 software. Findings Jamkesus Disabilitas has improved access to assistive technology (AT) and demonstrated inclusive care through its one-stop service. It also highlights the importance of consistent leadership in disability-inclusive health systems. However, challenges persist, including uneven AT quality, low coverage, limited availability, and inadequate data for evaluation and planning persisted. Moreover, the absence of inclusive features in the regular service means the scheme has not fully closed the equity gap in healthcare access for people with disabilities. Conclusion Jamkesus Disabilitas has expanded access to AT overlooked by the national health insurance (JKN). However, implementation should prioritise AT quality standards, financial and operational sustainability, and stronger data systems. Broader systemic reforms are also needed to embed disability inclusive practices in regular healthcare service delivery. Keywords Health equity, inclusive health system, social protection, health insurance, health financing

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Value-for-money of school feeding programs in sub-Saharan Africa: A multi-country cross-sectoral analysis

Ramponi, F.; Forzy, T.; Iversen, I.; Kim, S.; Durizzo, K.; Gautam, P.; Memirie, S. T.; Habtemichael, M.; Getnet, F.; Masamba, K.; Ndayitwayeko, W.-M.; Ntunzwenimana, M.; Assa, B. S. K.; Rieth, B.; Kamwi, G.; Ingula, S.; Uchezuba, D.; Macuacua, C.; Mindo, N.; Chioze, A.; Tostao, E.; Bundy, D. A. P.; Verguet, S.

2026-06-29 public and global health 10.64898/2026.06.24.26356172 medRxiv
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Introduction: School feeding programs (SFPs) can contribute to address undernutrition in low- and middle-income country settings while can simultaneously improve education outcomes and deliver social and economic benefits. However, evidence on their comprehensive value for money (VfM) remains limited. This study models the multi-sectoral impacts of SFPs across education, health, social protection, and the local agricultural economy in five sub-Saharan African countries, providing benefit-cost ratio (BCR) and VfM estimates to inform policy decisions. Methods: The analysis used secondary data from national reports, program budgets, and national household surveys. SFP impacts on education were assessed through changes in years of schooling and linked to lifetime income gains. Health impacts were quantified as averted anemia cases, converted into disability-adjusted life years (DALYs) and monetized using gross domestic product (GDP) per capita. Social protection benefits were measured as the in-kind value of school meals relative to household food expenditures, while local economic impacts were assessed through monetary transfers to smallholder farmers (SHFs) from local food procurement. BCRs were calculated considering education and health impacts, with additional VfM and expanded BCR estimates considering broader benefits and transfers. Results: Across countries, SFPs were associated with a cumulative gain of 0.6 to 2.3 years of schooling per beneficiary. Moreover, reductions in anemia cases are expected to avert between 4 to 51 DALYs per 1,000 beneficiaries. The BCR for education and health ranged between 3 and 31. Meals provided covered up to 28% of annual household food expenditures for low-income families. Local food procurement generated economic transfers between USD 7 and USD 15 per beneficiary per year to SHFs. Conclusion: SFPs demonstrate high VfM, offering significant educational, health, and economic benefits. Policymakers in sub-Saharan Africa should prioritize the expansion and scaling of SFPs to enhance educational attainment, improve health, and foster economic resilience, contributing to sustainable development.

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Strategies to enroll and retain low-income adolescent and young adult pregnant women in longitudinal studies: lessons learned from the AMOR project

Camara, S. M. A.; de Souza Barbosa, J. F.; Hipp, S.; Fernandes Macedo, S. G. G.; Sentell, T.; Bassani, D. G.; Domingues, M. R.; Pirkle, C. M.

2026-04-17 public and global health 10.64898/2026.04.13.26350540 medRxiv
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BackgroundProspective studies of pregnant adolescents are essencial to effectively address this global health priority. They help answer vital questions about their health, but such studies are uncommon due to the difficulty in retaining adolescents. This paper describes the successes and challenges of the research strategies used to ensure sufficient recruitment and retention of pregnant adolescents in a longitudinal study about adolescent childbearing in an under-resourced setting. MethodsThe Adolescence and Motherhood Research project was conducted in a rural region of Northeast Brazil in 2017-2019 and assessed 50 primigravids between 13-18 years (adolescents) and 50 primigravids between 23-28 years (young adults) during the first 16 weeks of pregnancy with two follow-ups (third trimester of pregnancy, and 4-6 weeks postpartum). Recruitment strategies involved engagement of health sector and community, as well as referrals from health care professionals and dissemination of the project in different locations. Retention strategies included maintaining contact with the participants between assessments and providing transportation for them to attend the follow-up procedures. ResultsRecruitment took 10 months to complete. A total of 78% of the participants were recruited from the primary health care units, mainly after referral from a health care provider. Retention reached 95% of the sample throughout the study (90%: adolescents; 98%: adults). ConclusionA combination of approaches is necessary to successfully recruit and retain youth in longitudinal studies and engaging local stakeholders may help to increase community-perceived legitimacy of the research. Working closely with front-line staff is essential when conducting research in rural low-income communities.

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Nutritional Status and Associated Factors Among Children Aged 6-24 Months at a Primary Health Care Centre in Conflict-Affected Gaza

Murtaja, L.; Abdeljawad, H.; Najim, A.; Rodgers, J.; Almukbel, R.; Mokbel, K.

2026-05-18 nutrition 10.64898/2026.05.12.26353044 medRxiv
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Background/Objectives: Children aged 6-24 months are highly vulnerable to malnutrition during conflict because they depend on breastfeeding, complementary feeding and functioning nutrition services. This study assessed nutritional status, socioeconomic correlates, maternal knowledge and primary health care centre (PHCC) nutrition service gaps in Gaza. Subjects/Methods: This cross-sectional study was conducted at Al-Daraj Martyrs Health Centre, one of the remaining functioning PHCCs in Gaza City during the study period, between late August and October 2025. Mother-child pairs were recruited by convenience sampling. Of 276 approached, 200 were included after non-response and exclusion of questionnaires with missing anthropometric data. Data came from structured interviews and medical records; haemoglobin results were available for 55 children. Results: Stunting affected 12.5% of children, underweight 20.1%, wasting 20.8%, and anaemia 63.6% of the haemoglobin-tested subsample. Underweight was associated with household food shortage (p=0.013) and previous malnutrition treatment (p=0.002), wasting with child age category (p=0.0024), and anaemia with paternal unemployment (p=0.020). Maternal knowledge and practice scores were positively correlated (r=0.177, p=0.012), but neither was independently associated with stunting or underweight in adjusted models. PHCC nutrition support was limited, with 71.0% of mothers reporting nurse-provided nutrition advice and 52.5% reporting growth-chart review. Conclusions: In this clinic-based sample from conflict-affected Gaza, malnutrition among children aged 6-24 months was substantial. The overall pattern suggests that nutritional risk was shaped more by structural deprivation and weakened PHCC support than by maternal knowledge alone. These findings underline the need to restore essential nutrition services and improve access to adequate food for young children.

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A qualitative study exploring opportunities for poverty alleviation interventions amongst people with severe mental health conditions in Eastern Cape, South Africa

Asher, L.; Rapiya, B.; Chiliza, B.; Hanlon, C.; Petersen, I.; Brooke-Sumner, C.

2026-05-18 public and global health 10.64898/2026.05.13.26353158 medRxiv
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Background People with severe mental health conditions (SMHC) and caregivers in South Africa experience high rates of poverty. The PRIZE feasibility trial found that recovery groups were broadly acceptable and feasible and potentially effective in reducing relapse. Addressing economic needs was identified as a means to increase impact. This study aimed to understand experiences of financial insecurity and acceptability of poverty alleviation interventions as an adjunct to psychosocial interventions amongst people with SMHC and caregivers. Methods We conducted two focus group discussions and 12 in-depth interviews in isiXhosa with a total of 14 people with SMHC and 13 caregivers who had participated in PRIZE in Eastern Cape Province, South Africa. An inductive thematic analysis was conducted. Results We identified four major themes. Theme 1: Financial insecurity as a defining influence on life. We found that financial security was crucial to recovery, through bringing status and dignity. However, participants experienced substantial financial insecurity, which impacted on social and mental wellbeing. Financial insecurity was entrenched due to fractured and violent communities, cycles of debt and stigma amongst employers. Theme 2: Government disability grants are not a panacea. Difficulties accessing disability grants included problems attending assessments and rejection of applications. Whilst they were generally welcomed, receipt of disability grants sometimes caused problems such as increased stigma and family disagreements about how the money should be spent. Theme 3: Group savings offer conditional hope if carefully managed. Several caregivers had longstanding experiences of stokvels (community-based credit unions). However, some were fearful of group members absconding with funds. Participants emphasised that trust, safety and fairness are essential for successful group savings. Theme 4: Income-generating activities are desired but need capital and come with safety concerns. Many had ideas and motivation for small businesses but stressed the need for financial capital, skills training and financial literacy support. There were serious concerns that owning a business or gaining wealth could make one a target of crime. Conclusion Poverty alleviation interventions could positively impact on the wellbeing of people with SMHC and caregivers in South Africa as an adjunct to psychosocial interventions and psychiatric care. Approaches could include supporting access to social protection or existing savings groups, and nesting new savings groups or income generation initiatives into psychosocial interventions. Any model would need to incorporate robust mechanisms to ensure the safety of participants. All approaches would be enhanced by parallel social and public health interventions to build social capital and reduce violence in neighbourhoods.

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Nutritional Knowledge And Associated Factors Among Pregnant Women In Ghana: A Cross-Sectional Study

Nkansah, M.; Salu, P. K.; Gyimah, L. A.

2026-04-17 nutrition 10.64898/2026.04.13.26350744 medRxiv
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BackgroundAdequate maternal nutritional knowledge is essential for healthy pregnancy outcomes, yet many pregnant women lack good nutritional knowledge. This study assessed nutritional knowledge and associated factors among pregnant women in the Krowor Municipality of Ghana. MethodsA facility-based cross-sectional study was conducted among pregnant women attending antenatal clinics in two public health facilities. Structured questionnaires were used to collect data on sociodemographic characteristics and nutritional knowledge. Data were analysed using descriptive statistics and chi-square tests at a 5% significance level. ResultsMost respondents demonstrated moderate nutritional knowledge (mean score =11.24 {+/-} 2.48), with 45% classified as having moderate knowledge. Income level (p = 0.00), education (p = 0.007), gestational age (p = 0.042), employment status (p = 0.007), and religion (p = 0.005) were significantly associated with nutritional knowledge. ConclusionThe study highlights notable gaps in nutritional knowledge among pregnant women in Krowor Municipality. Socioeconomic and obstetric factors strongly influenced nutritional knowledge. Strengthening antenatal nutrition counselling and improving socioeconomic support may help improve the nutritional knowledge of pregnant women.

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Impact of a Community Based Positive Deviance Hearth Intervention on Feeding Practices Among Malnourished Children Aged 6-59 Months in Bomet County Kenya

Koskei, G.; Karanja, S.; Ndugu, Z. W.; Anino, C. O.

2026-04-23 nutrition 10.64898/2026.04.18.26351171 medRxiv
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Child undernutrition remains a major public health challenge in Kenya. Suboptimal feeding practices contribute significantly to persistent underweight and stunting. This study evaluated the effect of a community-based Positive Deviance Hearth (PDH) intervention on feeding practices among children aged 6-59 months in Sub County within a County of study. The study adopted a two-group pretest-posttest randomized experimental study design conducted for six months period, among 84 caregiver-child pairs in intervention and control groups. A multi-stage sampling was employed to identify study settings and participants. Structured and pretested questionnaires, 24-hour food recall questionnaires and meal diversity questionnaires were used for data collection at pre-intervention and post-intervention periods. Data was analyzed using R software v.4.5.2. The differences between intervention and control groups at baseline and endline were assessed using difference-in-difference analysis, relevantly summarized using adjusted DID estimates, 95% confidence intervals and p-values, with p<0.05 considered significant. The PDH intervention significantly improved feeding practices among children 6-59 months. Meal frequency increased for 9-23 months (DiD = +1.4; 95% CI: 1.2-1.7; p = 0.034) and [&ge;]24 months (DiD = +1.2; 95% CI: 1.1-1.5; p = 0.017), and dietary diversity rose (DiD = +1.3; 95% CI: 1.1-1.9; p < 0.001). Nutrient-dense food consumption improved, including legumes (DiD = +32.6%; p < 0.001) and animal-source foods (DiD = +35.4%; p < 0.001). Energy and protein intake increased across all age groups (p < 0.05), and micronutrients--iron, vitamin A, vitamin C--also rose significantly (p < 0.05). The PDH intervention substantially improved caregiver feeding practices, increased dietary diversity, and enhanced macro- and micronutrient intake, demonstrating its effectiveness as a scalable, community-driven strategy for sustainably improving child nutrition in high-burden settings.

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Climate Change, Place, and Mental Health in Sub-Saharan Africa: A Multi-Country Analysis of Lived Experiences Following Extreme Weather Events

Mulopo, C.; Ndlovu, S. M. S.; Akinyi, L. J.; Muanido, A.; Kabre, W.; Ouedraogo, M.; Maivasse, C. M.; Jose, S. F.; Odero, H. O.; Mthembu, R.; Zuma, L.; Lindner, E.; Craig, M.; Traore, N.; Cumbe, V. F.; Wambua, G. N.; Omondi, E.; Wekesah, F. M.; Black, G. F.; Iwuji, C.; Treffry-Goatley, A.

2026-07-08 public and global health 10.64898/2026.06.25.26356208 medRxiv
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Background: Climate change is an escalating global health threat, with sub-Saharan Africa disproportionately affected due to entrenched spatial inequalities, high exposure to environmental hazards, and limited adaptive capacity. Increasingly frequent extreme weather events (EWEs), including floods and cyclones, are reshaping the material and social conditions of place, with implications for mental health and wellbeing. However, evidence remains limited, particularly multi-country qualitative research that examines how mental health impacts are produced through lived experiences of place in contexts of recurring environmental disruption and structural vulnerability. This study explored the mental health and wellbeing impacts of EWEs among individuals with lived experience of such events in Mozambique, Burkina Faso, South Africa, and Kenya, using participatory methods that centred community narratives and place-based accounts of everyday life. Methods: This qualitative study employed digital storytelling as a participatory visual method to examine how EWEs are experienced and narrated across diverse socio-spatial contexts. A total of 37 participants (8 to 10 per country) were recruited from rural, peri-urban, and informal urban settlements with recent exposure to flooding or cyclone events. Participants produced digital stories during facilitated five-day workshops. These narratives were analysed using inductive and deductive thematic analysis informed by Braun and Clarke's framework, with attention to the spatial and relational production of distress and coping. Results: Across Mozambique, Burkina Faso, South Africa, and Kenya, findings show that the mental health impacts of EWEs are deeply embedded in place-based conditions and are cyclical, cumulative, and relational rather than confined to discrete disaster events. Participants described how repeated environmental disruptions reconfigured everyday life in place, generating ongoing uncertainty, anticipatory anxiety during rainfall periods, and acute fear during floods and cyclones. Loss of housing, livelihoods, infrastructure, and social anchors of place contributed to enduring psychological distress, which was frequently reactivated by subsequent environmental cues such as heavy rain, wind, and deteriorating physical environments. Persistent anxiety, hypervigilance, sleep disturbance, and emotional distress were reported across all sites. While social and community networks constituted critical infrastructures of care within place, these were often simultaneously overwhelmed as entire communities experienced shared disruption. Limited and delayed institutional responses further compounded spatial and social precarity. Conclusions: This study provides a comparative participatory account of how EWEs shape mental health through their embeddedness in place across diverse sub-Saharan African contexts. The findings demonstrate that psychological distress is produced through the interaction of repeated environmental exposure, structural inequality, and disrupted place-based infrastructures of daily life, rather than emerging solely as a post-disaster outcome. These results underscore the need for climate-responsive mental health and psychosocial support that is integrated into place-based disaster risk governance, alongside strengthened social protection and community infrastructure that can sustain wellbeing in contexts of recurring environmental instability.

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On the robustness of ethnic and socio-cultural determinants of healthcare decision-making autonomy among Hausa, Fulani, and Kanuri women in Northern Nigeria.

OGUNETIMOJU, A. M.; AJEBORIOGBON, S. A.

2026-04-22 public and global health 10.64898/2026.04.21.26351355 medRxiv
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BackgroundWomens autonomy in healthcare decision-making has become one of the most critical yet inequitably distributed determinants of health outcomes, gender equity, and sustainable development worldwide. In Northern Nigeria, the presence of ethnic and socio-cultural inequality is frequently concealed by the aggregated statistics of a region. MethodsThis cross-sectional secondary analysis utilized the 2024 Nigeria Demographic and Health Survey. The sample included 9,998 married women (15-49 years) identifying as Hausa, Fulani, or Kanuri in Northern Nigeria. Healthcare autonomy was categorized as husband/partner alone, respondent alone, or joint decision-making. Analysis included weighted descriptive statistics, Rao-Scott adjusted chi-square tests for residential associations, and complex sample multinomial logistic regression to identify multivariable correlates while adjusting for sampling weights, strata, and clusters. ResultsMean age was 30.38 years. Most participants lacked formal education (69.6%) and resided in rural areas (72.0%). Husband-only decision-making predominated (72.6%), while 22.5% reported joint and 4.9% independent autonomy. Joint decision-making was significantly higher in urban (33.3%) than rural areas (18.3%; Adjusted F=50.892, p<0.001). In adjusted models (Reference: Kanuri), Hausa and Fulani women had substantially lower odds of joint decision-making relative to husband-only outcomes. Rural residence correlated with lower odds of both independent and joint agency. Notably, wealth status was not a significant predictor after adjustment (p > 0.05). ConclusionsEthnicity and residence are robust determinants of healthcare autonomy among women in Northern Nigeria, persisting regardless of education or wealth. This "socio-cultural paradox" suggests that economic interventions alone are insufficient. Policies must complement socioeconomic approaches with culturally responsive strategies addressing household power dynamics and entrenched social norms.

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Comparative analysis of simplified and standard protocols for managing moderate and severe acute malnutrition in outpatient services in Venezuela: a prospective cohort study

Hernandez, P.; Mata, C.; Lares, M.; Moran, M.; Gonzalez, Z.; Catarino, E.; Ramos, Y.; Varela, A.; Fautsch-Macias, Y.; Funnell, G.

2026-04-29 nutrition 10.64898/2026.04.27.26351902 medRxiv
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To provide adequate care to children with acute malnutrition, different management protocols have been in use, including the WHO standard guideline and a simplified protocol. The latter, used in Venezuela since 2020, has adopted three simplifications: 1) Expanded criteria for treatment admission; 2) Use of a single treatment product; 3) Simplified dosage: use of 2 sachets per day to treat SAM cases and 1 sachet per day to address MAM cases, regardless of weight. Our study compares the effectiveness, length of stay and programmatic costs of the simplified protocol and the WHO standard guideline in addressing acute malnutrition in children aged 6-59 months in Venezuela from February to August 2024. A total 229 children were enrolled in a prospective cohort study. Monitoring was continuous up to 16 weeks of treatment, evaluating key indicators including weight gain, recovery time, survival, recovery and default rates, number of sachets of RUTF consumed and implementation costs. Baseline characteristics were similar between cohorts, with most cases being moderate in both the standard (90.9%) and simplified (86.6%) cohorts. Both protocols demonstrated similar anthropometric improvements and recovery trajectories throughout follow-up, with no significant differences (p > 0.05). However, the simplified protocol showed higher recovery rates overall for MAM and SAM (70.1% vs 59.4%, p=0.031), although default rates remained high in both protocols (24.8% in the standard protocol vs. 18.7% in the simplified protocol). The simplified protocol presented reduced costs by 15% ($133 vs $157 per recovered child). These results suggest that the simplified protocol, using a single product and an adapted dosage, is as effective as the standard protocol for treating children with acute malnutrition in Venezuela. The findings support wider implementation of the simplified protocol particularly in resource-limited settings. Further research is needed to optimize protocols and improve adherence to reduce default rates.

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Analyzing Access to Surgical Services in Central Equatoria State, South Sudan: A Baseline Cross-Sectional Assessment to Inform National Surgical Policy and Planning

Deng, M. D. A.; Alayande, B. T.; Sheferaw, E. D.; Ngutete Mukundwa, P.; Fofanah, T.; Peter, M. B.; Kuron, D.; Bekele, A.; Dau, A. D.

2026-04-22 public and global health 10.64898/2026.04.20.26351353 medRxiv
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BackgroundAccess to safe, equitable, and affordable surgical and anesthesia care is critical to reducing the burden of surgical diseases in Africa. To understand the state of access in South Sudan, we conducted a baseline assessment of surgical services in Central Equatoria State (CES) in May 2024. ObjectivesThis study aimed to survey public healthcare facilities in CES capable of providing essential surgical services. We used the capacity to perform cesarean section, laparotomy, and open fracture management--Bellwether procedures--as a proxy for assessing workforce, infrastructure, financing, information management, and service delivery. MethodsWe used a validated and contextualized Surgical Assessment Tool developed by the Harvard Program on Global Surgery and Social Change and the World Health Organization. Data were collected at the facility level and summarized descriptively using percentages, means (standard deviations), medians (minimum, maximum), and visualized in graphs, charts, and tables. ResultsAll three public health facilities assessed could perform Bellwether procedures for their catchment populations. However, workforce availability, financing, and surgical infrastructure were major constraints. The surgical workforce density was 2.27 surgical, anesthesia, and obstetric specialists per 100,000 population. Specialized procedures--such as repair of cleft lip and palate, clubfoot, and hydrocephalus shunt--were unavailable at all sites. None had magnetic resonance imaging (MRI) machines. The total average annual facility budget was $918,850, ranging from $3,960 to $800,000 at the teaching hospital--insufficient for proper operations. ConclusionWhile Bellwether procedures are routinely performed, access to quality and affordable care is compromised by deficits in workforce, financing, and infrastructure. We recommend that the Ministry of Health scale this survey nationally and develop a surgical policy and strategic plan focused on improving infrastructure, workforce, and financing for surgical and anesthesia care in South Sudan.

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The Acceptability of Three Co-Created Peer Support Interventions for People Living with Leprosy Reactions in Indonesia: A Mixed-Methods Pilot Study

Putri, A. I.; Walker, S. L.; Agusni, R. I.; Alinda, M. D.; Kusumaputra, B. H.; Listiawan, M. J.; Peters, R. M. H.; Zweekhorst, M. B. M.

2026-06-12 health systems and quality improvement 10.64898/2026.06.10.26355364 medRxiv
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Background: Leprosy reactions (LR) are immune-mediated complications associated with disability, emotional distress, and social isolation. We identified a gap in affected-individual-informed interventions that aim to improve the management of LR in healthcare settings. To address this gap, we assessed the acceptability of three peer-support interventions co-created with people affected by LR in Indonesia. Methods: Using an interactive learning and action approach, we co-created peer counselling, telesupport groups, and participatory video interventions which were piloted in an urban hospital and 13 rural community clinics. A mixed-methods design was applied with interviews, focus group discussions, and pre-post assessments involving four participant groups. Data were analyzed thematically using an acceptability framework. Results: One hundred participants were enrolled, and 92 completed the pilot intervention between November 2022 and July 2023. Qualitative findings showed that all interventions were acceptable. Peer counselling provided emotional reassurance through shared experiences and was perceived as trustworthy and supportive. Perceived burdens differed by setting, with time constraints in urban facilities and geographical barriers in rural clinics. Knowledge improved significantly among participants of peer counselling and telesupport groups in rural settings. Telesupport groups facilitated connection, information exchange, and continuity of care. Digital access and literacy limited participation for some, particularly in rural areas. The participatory video was perceived as reassuring and informative. Improvements in knowledge, attitude, practices, and mental well-being domain scores were observed among urban participants, but responses in rural settings showed less change. Participants and co-implementers reported increased self-efficacy, participants confidence to perform required behaviors within peer support interventions, with effects shaped by intervention and setting. Conclusions: The three co-created peer-support interventions were acceptable for individuals with LR in diverse healthcare settings. These outcomes highlight the importance and effectiveness of selective, and context-sensitive implementation of one or more peer-support modalities.

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Exploring the Factors Influencing Resilience Among Returnee Migrants in Nigeria

Awoleye, O. J.; Uthman, K. A.; Sanni, O. F.; Uchendu, F. N.

2026-07-06 public and global health 10.64898/2026.07.02.26357141 medRxiv
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Background: Returnee migrants in Nigeria often face significant psychosocial and economic challenges during reintegration, necessitating resilience to adapt and recover. This study examined factors influencing resilience among returnee migrants in Nigeria. Methodology: A mixed methods design was employed, involving 1316 returnees selected through multistage sampling across Nigeria six geopolitical zones. Quantitative data were collected using the Connor Davidson Resilience Scale and analyzed using SPSS version 28. Qualitative data was obtained through eight focus group discussions and analyzed thematically. Result: Social support from family and friends was inconsistent (70.8% reported occasional support), while community support was largely absent (85.9%). Financial insecurity was widespread (gt 90%). Male gender (AOR = 6.092, plt 0.001), ethnicity, and higher education were significant predictors of resilience. Qualitative findings highlighted the role of family support, faith, adaptive coping, and skill acquisition in strengthening resilience. Conclusion: Resilience among returnee migrants in Nigeria is limited by weak structural and economic support, despite moderate personal coping capacity. Strengthening economic opportunities, community integration, and access to mental health services is essential for sustainable reintegration. Keywords: Returnee migrants, resilience, Reintegration, and psychosocial factors.

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Sociodemographic determinants of maternal health indicators in conflict-affected counties of Kenya: secondary analysis of data from the 2022 Kenya demographic and health survey

Wandji Djouonang, B.; Olungah, C. O.; Atsali, E.; Kihara, A.-B.; Omanwa, K.; Obimbo, M. M.; Ogengo, J.

2026-04-24 public and global health 10.64898/2026.04.22.26351520 medRxiv
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ObjectiveTo analyse sociodemographic determinants of maternal health indicators in Kenyas conflict-affected regions. MethodsA cross-sectional secondary analysis of the 2022 Kenya Demographic and Health Survey (KDHS) was conducted. Conflict-affected counties were identified using ACLED (>25 fatalities). The sample included 1,060 women aged 15-49 years. Outcomes were adequate antenatal care (ANC 4+), facility delivery, and skilled birth attendance (SBA). Predictors included age, education, wealth, employment, residence, and county; intimate partner violence was adjusted for. Weighted descriptive statistics, chi-square tests, and multivariable logistic regression were applied (p<0.05). ResultsSix counties met conflict criteria. While 90.2% of women attended at least one ANC visit, only 53.5% achieved ANC 4+. Facility delivery and SBA were 68.2% and 72.2%, respectively. Adolescents (15-19) were least likely to attain adequate ANC; women aged 20-24 had higher odds (aOR=1.83; 95% CI: 1.01-3.34). Education strongly predicted outcomes: higher education increased ANC 4+ (aOR=2.74; 95% CI: 1.19-6.34) and facility delivery (aOR=2.72; 95% CI: 1.15-6.47). Wealth showed strong gradients: middle quintile increased facility delivery (aOR=5.50; 95% CI: 2.14-14.14), while richer quintile increased SBA (aOR=11.04; 95% CI: 2.06-59.25). Rural residence reduced facility delivery (aOR=0.32) and SBA (aOR=0.22). County disparities persisted. IPV was not independently associated. ConclusionMaternal health indicators in conflict-affected Kenya follow a marked inequity gradient. Adolescents, rural residents, and socioeconomically disadvantaged women are most excluded. Strengthening adolescent ANC continuity, reducing rural access barriers, and investing in education and economic empowerment are critical for improving outcomes.